Published November 20, 2025 | Version v1
Dataset Open

Impact of stress-regulated growth factor signaling on lipidomic profiles

Authors/Creators

  • 1. ROR icon Universität Innsbruck
  • 2. ROR icon University of Graz
  • 3. ROR icon Friedrich Schiller University Jena

Contributors

  • 1. ROR icon Universität Innsbruck
  • 2. ROR icon Friedrich Schiller University Jena
  • 3. ROR icon University of Graz
  • 4. ROR icon Leibniz Institute on Aging – Fritz Lipmann Institute
  • 5. ROR icon Paracelsus Medical University
  • 6. ROR icon National Center For Global Health and Medicine
  • 7. ROR icon University of Tokyo

Description

Cytotoxic stress and survival signaling mediated by growth factors are intricately intertwined, influencing cellular lipid metabolism and composition through mechanisms that remain incompletely understood. These datasets present changes in lipidomic profiles across multiple experimental models (based on fibroblasts, cancer cell lines, primary cells, and C. elegans), providing insights into the underlying biological processes. Metadata, including details on sample treatment, preparation, and analytical methods, are embedded within the data files.

Files

ACC_Knockdown.zip

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Additional details

Funding

FWF Austrian Science Fund
Lipid metabolic mechanisms in EMT/ZEB1-dependent ferroptosis 10.55776/P36299
Phospholipid Research Center
AKO-2015-037/1-1, AKO-2019-070/2-1, AKO-2O22-100/2-2 AKO-2015-037/1-1, AKO-2019-070/2-1, AKO-2O22-100/2-2
Friedrich Schiller University Jena
DRM/2013-05 and 2.7-05 DRM/2013-05 and 2.7-05
Deutsche Forschungsgemeinschaft
GRK 1715 and KO 4589/4-1 GRK 1715 and KO 4589/4-1